Publications

Several publications have been published in international journals.

In addition posters have been published on several major international HPV-conferences.

Publications on PreTect HPV-Proofer and HPV

Basu P et al. (2009) Human Papillomavirus Genotype Distribution in Cervical Cancer in India: Results from a Multi-center Study, Asian Pacific Journal of Cancer Prevention, Vol 10, 2009, 27-34

Szarewski A et al. (2008) Comparison of Predictors for High-Grade Cervical Intraepithelial Neoplasia in Women with Abnormal Smears, Cancer Epidemiol Biomarkers Prev. 2008;17(11) November 2008

Keegan H et al. (2008) Comparison of HPV detection technologies: Hybrid capture 2, PreTecttrade mark HPV-Proofer and analysis of HPV DNA viral load in HPV16, HPV18 and HPV33 E6/E7 mRNA positive specimens, J Virol Methods

Holm R et al. (2008) Human Papillomavirus DNA and E6/E7 mRNA Status in Relation to Survival of Patients Treated for Cervical Squamous Cell Carcinoma, The Open Virology Journal, 2008, 2, 74-81

Dixon EP et al. (2008) Isolation of RNA from residual BD SurePathtrade mark liquid-based cytology specimens and detection of HPV E6/E7 mRNA using the PreTecttrade mark HPV-Proofer assay, J Virol Methods. 2008 Sep 19

Kraus I et al. (2008) The Majority of Viral-Cellular Fusion Transcripts in Cervical Carcinomas Cotranscribe Cellular Sequences of Known or Predicted Genes. Cancer Res. 2008 Apr 1;68(7):2514-22

Varnai A et al. (2008) Predictive testing of early cervical pre-cancer by detecting human papillomavirus E6/E7 mRNA in cervical cytologies up to high-grade squamous intraepithelial lesions: Diagnostic and prognostic implications. ONCOLOGY REPORTS 19: 457-465

Rosini S et al. (2007) Management and triage of women with human papillomavirus infection in follow-up for low-grade cervical disease: Association of HPV-DNA and RNA-based methods. International Journal of Immunopathology and Pharmacology, Vol. 20, no. 2, 341-347

Molden et al. (2007) PreTect™ HPV-Proofer: Real-time detection and typing of E6/E7 mRNA from carcinogenic human papillomaviruses. Journal of Virological Methods, Volume 142, Issues 1-2, June 2007, Pages 204-212

Andersson S et al. (2006) Expression of E6/E7 mRNA from 'high risk' human papillomavirus in relation to CIN grade, viral load and p16INK4a. Int J Oncol. 2006 Sep;29(3):705-11

Kraus I et al. (2006) Presence of E6 and E7 mRNA from Human Papillomavirus Types 16, 18, 31, 33, and 45 in the Majority of Cervical Carcinomas. Journal of Clinical Microbiology, April 2006, p. 1310-1317, Vol. 44, No. 4

Molden T et al. (2005) Human papillomavirus E6/E7 mRNA expression in women younger than 30 years of age. Gynecol Oncol. 2006 Jan;100(1):95-100. Epub 2005 Sep 8

Cuschieri K et al. (2005) Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid based cytology medium. J Virol Methods. 2005 Mar;124(1-2):211-5

Lie AK et al. (2005) DNA VERSUS RNA BASED METHODS FOR HUMAN PAPILLOMAVIRUS DETECTION IN CERVICAL NEOPLASIA. Gynecologic Oncology, Volume 97, Issue 3 , June 2005, Pages 908-915

Molden T et al. (2005) Predicting CIN2+ when detecting HPV mRNA and DNA by PreTect HPV-proofer and consensus PCR: A 2-year follow-up of women with ASCUS or LSIL pap smear. Int J Cancer. 2005 Jan 11;114(6):973-976

Molden T et al. (2005) Comparison of Human Papillomavirus Messenger RNA and DNA Detection: A Cross-sectional Study of 4,136 Women >30 Years of Age with a 2-Year Follow-up of High-Grade Squamous Intraepithelial Lesion. Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):367-72

Cuschieri K et al. (2004) Human papillomavirus type specific DNA and RNA persistence -implications for cervical disease progression and monitoring. J Med Virol. 2004 May;73(1):65-70

Kraus I et al. (2004) Human papillomavirus oncogenic expression in the dysplastic portio; an investigation of biopsies from 190 cervical cones. Br J Cancer. 2004 Apr 5;90(7):1407-13

Publications on BioMEMS

Anja Gulliksen, Lars Solli, Frank Karlsen, Henrik Rogne, Eivind Hovig, Trine Nordstrøm and Reidun Sirevåg, Real-time Nucleic Acid Sequence-Based Amplification in Nanoliter Volumes, Analytical Chemistry, 2004, 76, 9 – 14

Anja Gulliksen, Lars Solli, Klaus Stefan Drese, Olaf Sörensen, Frank Karlsen, Henrik Rogne, Eivind Hovig and Reidun Sirevåg, Parallel Nanoliter Detection of Cancer Markers using Polymer Microchips, Lab. Chip., 2005, 5(4), 416 - 420

Some published posters

22nd. International Papillomavirus Conference, Vancouver, BC, Canada, April 30 - May 6, 2005
1.
 Irene Kraus, Corina Ziegert, Tatiana Koch, Achim Schneider, Matthias Dürst: Hypothetical genes are frequent targets of HPV DNA integration in cervical carcinomas.
2.
 Tor Molden, Irene Kraus, Ruth Holm, Frank Karlsen, A. Kathrine Lie, Gunnar B. Kristensen, Bjørn Hagmar, Hanne Skomedal: Presence of different HPV 16 RNA transcripts in normal cells compared to CIN2, CIN3 and SCC biopsies.
3.
 Frank Karlsen, Geir Morland and Hanne Skomedal: Difference in coverage rate between DNA- and mRNA-based methods for HPV positive invasive cervical carcinoma samples - A summary of studies.
4.
 Frank Karlsen and Hanne Skomedal: Persistent transforming HPV infection may correlate with persistent histologically defined CIN II+.
5.
 Tor Molden, Trine Nordstrøm, Linda Kristiansen, Irene Kraus, Frank Karlsen and Hanne Skomedal: Analytical performance of the PreTect HPV-Proofer assay for detection of E6/E7 mRNA expression and typing of 5 high-risk HPVs.
6.
 Petter Grønn, Frank Karlsen, Inger-Marie Falang and Hanne Skomedal: High quality mRNA can be extracted from routinely collected cervical samples by several commercially available methods and detected by PreTect HPV-Proofer.
7.
 Hovland S, Lie AK, Risberg B, Ryd W, Borge B, Berle E, Skomedal H, Kadima T, Batumbola L, Kyembwa ML, Bilayi E, Mukwege D, Chirimwami B, Kashongwe JP, Mvula M, Falang BM, and Karlsen F: Calculations from a High Risk Population study.
8.
 H. Haaheim, M. Nygård, T.J. Gutteberg, G.S. Simonsen, J.F. Nygård: HPV E6/E7 mRNA detection and concurrent Pap smear cytology in a population of 19,152 Norwegian women aged 13 to 87 years.
9.
 Corina Ziegert, Irene Kraus, Svetlana Vinokourova, Magnus von Knebel Doeberitz, Achim Schneider Peter Hillemanns, Matthias Dürst: Studies on the Stabilityof Viral and Viral-Cellular Fusion Transcripts Derived from HR-HPV Positive Cervical Carcinomas.
10.
 S. Vinokurova, I. Kraus, C. Ziegert, N. Wentzensen, P. Melsheimer, M. Dürst, A. Schneider, M. von Knebel Doeberitz: Integration Frequencies of Viral Genomes Differ Among Cervical Cancers Infected by Different High Risk HPV Types: Evidence for Differences in the Oncogenic Potential of Individual HPV Types.

21st International Papillomavirus Conference, 20-26 February 2004, Mexico City, Mexico:

1.

Lie AK, Risberg B, Sandstad B, Delabie J, Hagen B, Onsrud M, Thoresen S: DNA versus RNA based methods for HPV testing in Norway. Evaluation of Hybrid Capture II and PreTect HPV-Proofer, a validation study.
2.

Molden T, Kraus I, Karlsen F, Skomedal H, Nygård J, Hagmar B: E6 and E7 mRNA expression from carcinogenic Human papillomavirus (HPV) in 4136 cervical samples collected from an outpatient population.
3.

Karlsen F: The potential of RNA as a target for molecular diagnostics in cervical carcinoma screening.
4.

Bjerre P, Hagmar B, Dillner L, Edvardsson H, Mellinger I, Karlsson E, Karlsen F, Skomedal H, Andersson-Ellstrøm A: HPV detection as follow-up of low-grade lesions in the Swedish gynaecological screening program. Comparison between Hybrid Capture II and the RNA-based PreTect HPV-Proofer Assay.

<Back>